Regional Leaders in Prostate Cancer Radiotherapy

Beat Prostate Cancer
Without Surgery

Modern radiation therapy — including SBRT and IMRT — cures localized prostate cancer as effectively as surgery, with no incisions, no hospital stay, and a lower risk of both incontinence and erectile dysfunction.Proven in a 15-year randomized trial • As few as 5 treatments • No downtime

97%+
15-Year Survival (ProtecT Trial)
5
Treatments Possible with SBRT
0
Incisions or Hospital Stays
15min
Typical Session Time
Call 727-343-0600
Prostate Cancer Radiation Therapy - Modern Linear Accelerator at WellSpring Oncology
The ProtecT Trial
Radiation matched surgery for survival at 15 years — with fewer urinary side effects
World-Class Treatment Options

Two Proven Paths, One Goal: Cure

Not long ago, prostate radiation meant seven to nine weeks of daily visits. Today, WellSpring Oncology delivers curative treatment in as few as five sessions — with precision that protects the tissue around the prostate.

Fastest Course

SBRT

Stereotactic Body Radiation Therapy

An ultra-precise, high-dose technique that completes curative treatment in just 5 sessions over about two weeks. Reserved for carefully selected patients — gland size, baseline urinary function, and cancer risk group all must qualify, and many men do not.

  • 5 treatments instead of 20–45
  • Each visit takes under 30 minutes
  • Daily IGRT confirms millimeter-level accuracy at every session
  • Candidacy is determined at consultation — not every man qualifies
Modern Standard

IMRT

Hypofractionated

Intensity-modulated beams sculpt dose around the bladder, rectum, and nerves while a moderately higher daily dose shortens the course to about 4–5½ weeks — proven equivalent to longer schedules in randomized trials.

  • 20–28 treatments over 4–5½ weeks
  • Randomized trials confirm equal cure rates to longer courses
  • Daily IGRT targets the prostate before every treatment
  • Excellent balance of speed and gentleness
Time-Tested

IMRT

Conventional Fractionation

The most extensively proven curative approach, delivering a gentle daily dose over 8–9 weeks. The right choice for larger glands, significant baseline urinary symptoms, or higher-risk disease requiring wider treatment fields.

  • Gentlest dose per visit — well tolerated at any age
  • Preferred when urinary symptoms or gland size limit shorter courses
  • Daily IGRT keeps precision high across the full course
  • Combines seamlessly with hormone therapy when needed

The Precision Behind Every Treatment

Curing the cancer is only half the mission. The other half is protecting everything around it.

Image-Guided Targeting (IGRT)

Daily imaging locates the prostate before every treatment, so the beam follows the target — not the other way around. Accuracy is measured in millimeters.

Hydrogel Rectal Spacer

A dissolvable gel placed between the prostate and rectum in a brief office procedure pushes healthy tissue out of the radiation field, sharply reducing rectal side effects.

MRI-Based Planning

MRI fusion gives us a clearer look inside the prostate than CT alone, letting us shape dose precisely around the tumor while protecting nerves, bladder, and rectum.

Personalized Risk Assessment

Genomic testing, PSA kinetics, and modern staging scans help us match treatment intensity to your specific cancer — including when hormone therapy adds benefit and when it can be safely avoided.

Focal Microboost for High-Risk Cancer

For high-risk disease, we can escalate dose precisely to the MRI-visible dominant tumor nodule — a "microboost" shown in the 10-year FLAME trial to improve cancer control without increasing side effects.

Landmark Evidence: The ProtecT Trial

Radiation vs. Surgery: The Data

The ProtecT trial randomized 1,643 men with localized prostate cancer to radiation, surgery, or active monitoring — then followed them for 15 years. Published in the New England Journal of Medicine, it remains the definitive head-to-head comparison.

1,643
Men Randomized
3
Treatment Arms
15 yrs
Median Follow-Up
NEJM
Published 2016 & 2023
Finding #1

Survival Was Virtually Identical

15-year prostate cancer survival was about 97% with both radiation and surgery. Radiation cured prostate cancer just as reliably as removing the prostate entirely.

97.1%Survival
Radiation Therapy
15-year cancer survival
97.8%Survival
Surgery
15-year cancer survival

No statistically significant difference in survival was found between radiation and surgery. Both treatments also reduced the risk of the cancer spreading (metastasis) by about half compared with monitoring alone — 5.0% with radiation vs. 4.7% with surgery vs. 9.4% with monitoring.

Finding #2

Quality of Life Was Not Identical

With cure rates equal, the patient-reported outcomes became the deciding factor — and they clearly favored radiation for urinary control and preservation of erectile function.

Urinary Leakage Requiring Pads

Men using absorbent pads at 6 months — the point of greatest difference (scale: 10 men = 100%)

Fewer is better

SurgeryWorse46%
4.6 in 10 men
Radiation TherapyBetter5%
0.5 in 10 men
Active Monitoring4%
0.4 in 10 men

Nearly 1 in 2 men needed pads six months after surgery, versus about 1 in 20 after radiation. Incontinence remained worse in the surgery group at every follow-up point in the trial.

Erections Firm Enough for Intercourse

Men reporting function at 6 years — the longest follow-up reported (scale: 10 men = 100%)

More is better

SurgeryWorse17%
1.7 in 10 men
Radiation TherapyBetter27%
2.7 in 10 men
Active Monitoring30%
3.0 in 10 men

Erectile function remained worse after surgery at every time point — the drop was steepest and most immediate (12% at 6 months), with the least recovery. At 6 years, radiation patients were far more likely to retain function.

Source: Donovan JL, et al. Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer (ProtecT). N Engl J Med 2016;375:1425–37

The Bottom Line from 15 Years of Evidence

If radiation cures prostate cancer as reliably as surgery — and it does — then the decision comes down to side effects, recovery, and quality of life. That's where modern radiotherapy shines. And remember: the ProtecT trial used 1990s-era radiation techniques. Today's image-guided IMRT and SBRT are dramatically more precise than what those patients received.

Sources: Hamdy FC, et al. N Engl J Med 2023;388:1547–58 · Hamdy FC, et al. N Engl J Med 2016;375:1415–24 · Donovan JL, et al. N Engl J Med 2016;375:1425–37

An Honest Comparison

Radiation or Surgery: Know Both Sides

National guidelines recommend every man with localized prostate cancer meet with both a urologist and a radiation oncologist before deciding. Here's the balanced picture we walk through with every patient.

Radiation (SBRT / IMRT)
Surgery (Prostatectomy)
Cure rate (localized cancer)
Equivalent to surgery — confirmed at 15 years in ProtecT
Equivalent to radiation
Anesthesia & hospital stay
None — outpatient visits, drive yourself homeAdvantage
General anesthesia, 1–2 day hospital stay, urinary catheter for 1–2 weeks
Recovery time
None — normal activity throughout treatmentAdvantage
Several weeks of restricted activity
Urinary incontinence
Uncommon (~5% pad use at 6 months); temporary urinary irritation is more typicalAdvantage
Common early (~46% pad use at 6 months); persists long-term for some men
Sexual function
Better preservation at every ProtecT time point — 27% vs 17% with intact erections at 6 yearsAdvantage
Steepest, most immediate decline (12% at 6 months); least recovery long-term
Bowel effects
Possible temporary irritation; hydrogel spacers now make this uncommon
RareAdvantage
Pathology information
Relies on biopsy and imaging
Full prostate specimen analyzed after removalAdvantage
If cancer returns
Salvage options available for selected patients
Radiation can often be given afterward

Our commitment: the right treatment for you, not for us

Surgery is the right answer for some men, and active surveillance is the right answer for others — many low-risk cancers don't need treatment at all. Our radiation oncologists will tell you honestly which path fits your cancer, your anatomy, and your priorities. If that answer isn't radiation, we'll say so.

Prostate cancer research and guidance

Stay current with source-linked prostate evidence

Read our patient guides on prostate SBRT, brachytherapy boost, proton therapy comparisons, hormone therapy, and the latest randomized trial results.

Interested in protons? New data shows no benefit over modern IMRT for prostate cancer. Read more about the COMPPARE study

Read radiotherapy news
Get a Second Opinion Before You Decide

A Prostate Cancer Diagnosis
Deserves Every Option

Most men make their treatment decision within weeks of diagnosis — often after meeting only a surgeon. Before you decide, hear what modern radiotherapy can offer: equal cure rates, no operation, and treatment measured in days, not weeks of recovery.

Fast, Convenient Courses

SBRT completes curative treatment in as few as 5 visits — each under 30 minutes, no downtime

Evidence-Backed Cure

15-year randomized data shows radiation matches surgery for survival — with fewer urinary side effects

Close to Home

World-class prostate radiotherapy in Pinellas Park — serving St. Petersburg and all of Tampa Bay

Why Men Choose Radiation at WellSpring

Equal
Cure Rate to Surgery
~9×
Lower Risk of Needing Pads at 6 Months
0
Hospital Stays or Incisions

Get the full picture before you decide — your treatment choice lasts a lifetime

Call today to schedule your prostate cancer consultation with our radiation oncologists